Products

Products

Alphazer®

 

Alphazer® is composed of a disposable drug cartridge that fits onto a hand-held reusable base. 

it generates soft mist based on a porous medium. Its distinctive technology enables nebulization of aqueous solutions via a handheld, breath-actuated device.


Comprising a durable unit and consumable disposable cartridge, not requiring cleaning, the Alphazer® presents a hassle-free, no maintenance “plug and play” device, for the delivery of active substances to the lungs. Moreover, the system generates a soft mist cloud which requires neither breath coordination nor manipulation from the part of the user.


The Alphazer® technology can be employed in localized lung deposition as well as in systemic drug delivery. It is suitable for a variety of potential applications.

 

The Alphazer® technology stands out from the crowd of existing products by its ability to produce droplet sizes ranging from sub-micron to microns, making it suitable to numerous potential applications.

 

The platform benefits from a solid intellectual property foundation consisting of seven patent families. The technology shows at its current stage that it can be employed in conventional therapies for local administration in both lung and nose.

 

Product Advantages:

 

  • Handheld
  • Small mass-median aerodynamic diameter (MMAD)
  • High fine particle fraction (FPF)
  • “Soft mist”
  • Disposable aerosolizing element eliminates the need for cleaning and minimizes contamination-associated risks

 

The Alphazer® platform offers a unique proposition for pharmaceutical companies that are currently in early stage clinical trials with new therapeutic entities (NTEs), intended to be delivered to the deep lung, including systemic delivery via the lungs.

 

  • The effect of the inhaled solution’s physiochemical properties on the aerosol produced by the Alphazer® platform has been thoroughly investigated and can be beneficial in formulating towards desired properties.
  • Physical factors such as air velocity and aerosolization times can be easily fine-tuned through the control unit and assist in adapting the device to the formulation.
  • The use of disposable aerosolization elements circumvents the need for device cleaning and maintenance during studies.

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